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International Journal of Preclinical and Clinical Research

Article

International Journal of Preclinical and Clinical Research

Year: 2021, Volume: 2, Issue: 1, Pages: 20-23

Case Report

Smoldering Vogt-Koyanagi-Harada disease with extra ocular involvement — A case report

Received Date:08 December 2020, Accepted Date:22 March 2021, Published Date:06 April 2021

Abstract

To report a case of smoldering vogt-koyanagi-harada disease with extraocular involvement. A 45-years-old male presented with diminished vision in BE for one 1 — week associated with redness, pain, watering, intolerance to light with tinnitus also gives a history of similar complaints, in the past 2years. Examination revealed both eye visual acuity CF1/2 meters. Slit-lamp examination showed conjunctival ingestion, mutton fat KP’s, sluggishly reactive pupil with multiple broken posterior synechaie. Fundus showed grade 2 vitreous cells with multiple opacities, diffuse retinochoroidal thickening with disc edema. Tonometry was 16 and 29 mmhg respectively. B-scan showed multiple vitreous echo’s, diffuse retino-choroidal complex thickening with multiple shallow serous retinal detachment. After routine investigations patient was started on topical and systemic steroids. Lumbar puncture showed 82% lymphocytic pleocytosis. The patient recovered well with 6/24 vision in BE with a resolution of fundus finding at 6week followup. High index of suspicion, timely diagnosis and management are crucial to prevent vision threatening complications in VKH disease.

Keywords: Vogtkoyanagiharada disease; retinochoroidal thickening; serous retinal detachment; tinnitus; CSF pleocytosis; systemic steroids

References

  1. Forster DJ, Green RL, Rao NA. Manifestations of VKH-Syndrome. AMJ OPHTHALMOL. 1991;111:380–322.
  2. Lavezzo MM, Sakata VM, Morita C, Rodriguez EE, Abdallah SF, Silva FTGd, et al. Orphanet Journal of Rare Diseases. 2016;11(29):1–21. doi: 10.1186/s13023-016-0412-4
  3. Frutos AR, Romero PR, Pérez SH, Escalona JRA, Martínez-Morillo M, Segura BT. Enfermedad de Vogt-Koyanagi-Harada. In: Seminarios de la Fundación Española de Reumatología. (Vol. 13, pp. 142-146) Elsevier BV. 2012. 10.1016/j.semreu.2012.07.004
  4. Esparza AMR, OAVG, OUSA. Vogt-Koyanagi-Harada Incomplete Disease: A Case Report. Intern Med. 2018;8(5):1000291. doi: 10.4172/2165-8048.1000291
  5. GAO, Rao NA. Vogt-Koyanagi-Harada disease. Surv Ophthalmol. 2017;62(1):1–25. doi: 10.1016/j.survophthal.2016.05.002
  6. Douglas A. Improving the diagnostic criteria for vogt-koyanagiharada disease. JAMA ophthalmology. 2018;136(9):1032–1033. doi: 10.1001/jamaophthalmol.2018.2657

Copyright

© 2021 Savitha & Padmajothi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Basaveshwara Medical College & Hospital, Chitradurga, Karnataka.

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