Rare ovarian neoplasm: Primary precursor B-cell Lymphoblastic Lymphoma involving bilateral ovaries

K S Prajna; R P Muktha; I Sandhya; T R Phillipose

doi:10.51131/IJPCCR/v1i1.1

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International Journal of Preclinical and Clinical Research

DOI: 10.51131/IJPCCR/v1i1.1

Year: 2020, Volume: 1, Issue: 1, Pages: 35-38

Case Report

Rare ovarian neoplasm: Primary precursor B-cell Lymphoblastic Lymphoma involving bilateral ovaries

K S Prajna^1*, R P Muktha², I Sandhya³, T R Phillipose⁴

¹ Assistant Professor, Department of Pathology, Basaveshwara Medical College and Research Hospital, Chitradurga, Karnataka, India
² Professor, A J Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India
³ Associate Professor, A J Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India
⁴ Professor and HOD, A J Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India

*Corresponding author
Email: [email protected]

Received Date:02 December 2020, Accepted Date:14 December 2020, Published Date:21 December 2020

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

The involvement of the ovary in lymphomatous processes is rare. However, in the female genital tract, the ovary is a frequent site to be involved by the hematological malignancies. Involvement of the ovary by malignant lymphoma can be primary or secondary and is discovered incidentally during a workup for abdominal or pelvic complaints. Most commonly occurring ovarian lymphoma is diffuse large B cell type, whereas the Precursor B Cell Lymphoblastic Lymphomas are extremely rare and previously only 5 cases have been reported. Here, we report a case of clinically suspected malignant ovarian tumor involving bilateral ovaries, which was diagnosed as a primary precursor B-LBL after surgery in a young female. This case highlights the need for careful evaluation of radiologic and morphologic features along with an extensive immunohistochemical panel to arrive at the correct final diagnosis to guide the chemotherapy.

Keywords: Non-Hodgkin Lymphoma; Primary Ovarian Precursor B-Cell Lymphoblastic Lymphoma; Primary ovarian lymphoma; Primary ovarian tumors

References

Yadav R, Sharma MC, Karak AK, Agarwal N, Kumar R, Kumar L. Natural history of primary precursor B lymphoblastic lymphoma of the ovary: Report of a rare case. Journal of Obstetrics and Gynaecology Research. 2013;39(2):611–616. doi: 10.1111/j.1447-0756.2012.01984.x
Ganesan P, Joel A, Sundersingh S, Radhakrishnan V, Ganesan T, Sagar T. Primary B-cell lymphoblastic lymphoma of the ovary. Indian Journal of Medical and Paediatric Oncology. 2018;39(3):418. doi: 10.4103/ijmpo.ijmpo_144_16
Iyengar P, Ismiil N, Deodhare S. Precursor B-cell Lymphoblastic Lymphoma of the Ovaries: An Immunohistochemical Study and Review of the Literature. International Journal of Gynecological Pathology. 2004;23(2):193–197. doi: 10.1097/00004347-200404000-00017
Piura B, Bar-David J, Glezerman M, Zirkin HJ. Bilateral ovarian involvement as the only manifestation of malignant lymphoma. Journal of Surgical Oncology. 1986;33(2):126–128. doi: 10.1002/jso.2930330216
Vang R, Medeiros LJ, Warnke RA, Higgins JP, Deavers MT. Ovarian Non-Hodgkin’s Lymphoma: A Clinicopathologic Study of Eight Primary Cases. Modern Pathology. 2001;14(11):1093–1099. doi: 10.1038/modpathol.3880442
Sakurai N, Tateoka K, Taguchi J, Terada T. Primary Precursor B-cell Lymphoblastic Lymphoma of the Ovary: Case Report and Review of the Literature. International Journal of Gynecological Pathology. 2008;27(3):412–417. doi: 10.1097/pgp.0b013e31815ea7e3
Crasta J, Vallikad E. Ovarian lymphoma. Indian Journal of Medical and Paediatric Oncology. 2009;30(1):28. doi: 10.4103/0971-5851.56333
Fox H, More JRS. Primary malignant lymphoma of the uterus. Journal of Clinical Pathology. 1965;18(6):723–728. doi: 10.1136/jcp.18.6.723
Kaur N, Kaushal V, Kaushik R, Chahal J, Gulati A. Non-Hodgkin′s lymphoma presenting as an ovarian mass. Clinical Cancer Investigation Journal. 2014;3(3):231. doi: 10.4103/2278-0513.132117

Copyright

© 2020 Prajna et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Published By Basaveshwara Medical College & Hospital, Chitradurga, Karnataka.